Researchers at the University of Pennsylvania have developed fPE7max, a gene-editing tool built specifically for filamentous fungi, achieving editing efficiency approaching 90%. By using fPE7max to activate a master regulatory gene called laeA, the team awakened silent biosynthetic pathways across multiple fungal species, yielding eight molecules entirely new to science. Three of those molecules showed early anti-cancer properties in laboratory tests, including one with selec

A filamentous fungus isolated from sugarcane waste can simultaneously clean up toxic filter mud and generate usable bioelectricity, offering a practical solution for small-scale jaggery producers with little waste infrastructure.